I'm building myself a nice setup with a massive amount of screen real estate. Since I had/have problems with video drivers in the past. I'm asking for advise here first.

I want to connect at least six screens. like this: 6 screen setup

What are the best options? What are the pitfalls?
I preferably would not like to use closed binary blob drivers.

usecase scenario:
I'm writing a piece of software that has to interact with other systems.
I would like to be able to see all of those systems, my code, lots of log files and
documentation without the need to swap windows/screens. To just better see what im doing.

UPDATE

I recently updated to ubuntu 14.04 and my radeon HD7880 with six mini hd outputs just worked out of the box without manual binary driver downloads etc. hardeware acceleration worked to! YAY!