I guess the title says it all... Any ideas as to why? I tried removing potentially offending 32-bit libs (this is a 32-bit title) inside the game's lib32/ folder (I already have 32-bit libs installed). Alas, no dice. The worst part is that the game immediately exits when started without reporting a single error. All suggested fixes on the Frozenbyte forums have yielded no progress.
On a somewhat related topic, other games also exhibit problems, like Crayon Physics Deluxe.