I previously had this working with Ubuntu 10.x, and just recently upgraded to 12.04 (64 bit).

I had installed the driver from Epson: epson-inkjet-printer-escpr_1.2.0-1lsb3.2_i386.deb, and now also tried: epson-inkjet-printer-escpr_1.2.2-1lsb3.2_i386.deb but neither worked.

> sudo dpkg -i epson-inkjet-printer-escpr_1.2.2-1lsb3.2_i386.deb

(Reading database ... 753018 files and directories currently installed.)

Preparing to replace epson-inkjet-printer-escpr:i386 1.2.2-1lsb3.2 (using epson-inkjet-printer-escpr_1.2.2-1lsb3.2_i386.deb) ...

Unpacking replacement epson-inkjet-printer-escpr:i386 ...

cups stop/waiting

cups start/running, process 28199

dpkg: dependency problems prevent configuration of epson-inkjet-printer-escpr:i386:

 epson-inkjet-printer-escpr:i386 depends on lsb (>= 3.2).

dpkg: error processing epson-inkjet-printer-escpr:i386 (--install):

 dependency problems - leaving unconfigured

Processing triggers for libc-bin ...

ldconfig deferred processing now taking place

Errors were encountered while processing:

 epson-inkjet-printer-escpr:i386

The issue seems to be:
epson-inkjet-printer-escpr:i386 depends on lsb (>= 3.2).

I have lsb 4.0 installed, but maybe it's not the i386 version?

> dpkg -l | grep lsb

iU  epson-inkjet-printer-escpr:i386                          1.2.2-1lsb3.2                                   Epson Inkjet Printer Driver (ESC/P-R) for Linux

ii  lsb                                                      4.0-0ubuntu20.2                                 Linux Standard Base 4.0 support package

ii  lsb-base                                                 4.0-0ubuntu20.2                                 Linux Standard Base 4.0 init script functionality

ii  lsb-core                                                 4.0-0ubuntu20.2                                 Linux Standard Base 4.0 core support package

ii  lsb-cxx                                                  4.0-0ubuntu20.2                                 Linux Standard Base 4.0 C++ support package

ii  lsb-desktop                                              4.0-0ubuntu20.2                                 Linux Standard Base 4.0 Desktop support package

ii  lsb-graphics                                             4.0-0ubuntu20.2                                 Linux Standard Base 4.0 graphics support package

ii  lsb-printing                                             4.0-0ubuntu20.2                                 Linux Standard Base 4.0 Printing package

ii  lsb-release                                              4.0-0ubuntu20.2                                 Linux Standard Base version reporting utility

I have also run sudo apt-get -f install to no avail.

This was for the "Download Printer Driver ESC/P-R Driver (generic driver)"

Thank you!