I just did a fresh install of Ubuntu 22.04 and it broke support for CH340 USB to serial adapter based devices. (support was native in 20.04)
When I do /$ ls /dev there is no ttyUSB0 entry in the list.

If I do /$ lsusb I do get : Bus 003 Device 002: ID 1a86:7523 QinHeng Electronics CH340 serial converter

If I do /$ lsmod I can see the right module is loaded : ch34x 24576 0

I tried to manually create the node with mknod /dev/ttyUSB0 c 188 0 and chmod it to 777 but it doesn't work either.

Any help is welcome :)